1B mood disorders tute :// Flashcards

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1
Q

What are differentials to consider for depression and mania?

A
  • Bipolar disorder vs unipolar depression
  • Bipolar disorder vs borderline personality disorder/EUPD
  • Depression vs psychotic prodrome
  • Psychotic depression vs schizoaffective disorder (depressive type)
  • Mania vs schizoaffective disorder (manic type)
  • Mania vs Attention Deficit Hyperactivity Disorder
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2
Q

Why is there a therapeutic relevance to the distinction between bipolar and unipolar?

A

Because of antidepressants:

  • Appear to be mostly ineffective in acute bipolar depression and in prophylaxis
  • Can cause acute manic/hypomanic episodes
  • Have been shown to worsen the long-term course of bipolar illness in some subjects, especially those with a rapid-cycling course (>4 mood episodes in 12 months)
  • In rapid-cycling cases they appear to lead to more mood episodes, including depressive states
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