1B mood disorders tute ://

Question 1

What are differentials to consider for depression and mania?

Answer 1

• Bipolar disorder vs unipolar depression
• Bipolar disorder vs borderline personality disorder/EUPD
• Depression vs psychotic prodrome
• Psychotic depression vs schizoaffective disorder (depressive type)
• Mania vs schizoaffective disorder (manic type)
• Mania vs Attention Deficit Hyperactivity Disorder

Question 2

Why is there a therapeutic relevance to the distinction between bipolar and unipolar?

Answer 2

Because of antidepressants:

• Appear to be mostly ineffective in acute bipolar depression and in prophylaxis
• Can cause acute manic/hypomanic episodes
• Have been shown to worsen the long-term course of bipolar illness in some subjects, especially those with a rapid-cycling course (>4 mood episodes in 12 months)
• In rapid-cycling cases they appear to lead to more mood episodes, including depressive states

Question 3

Answer 3

Question 4

Answer 4

Question 5

Answer 5