CLINICAL CHEM Flashcards
- Which of the following refers to the correctness of a measurement or closeness with which the measurement comes to the true value?
a. Precision
b. Sensitivity
c. Accuracy
d. Specificity
e. Reliability
c. Accuracy
- Which of the following refers to the ability of an analytical procedure to
measure small amount of a component?
a. Accuracy
b. Sensitivity
c. Reliability
d. Precision
e. reliability
b. Sensitivity
- Which of the following refers to an abrupt change which may be observed
when there is sudden development of certain analytical problem?
a. Dispersion
b. Trend
c. Shift
d. Random error
e. Systematic error
e. Systematic error
- The best method in determining the presence of drugs in serum and urine is
a. Gas-chromatography-mass spectrometry (GC-MS)
b. Atomic absorption-spectrophotometry
c. High pressure liquid chromatography
d. Thin layer chromatography
a. Gas-chromatography-mass spectrometry (GC-MS)
- The advantages of ezymatic methods over chemical methods in serum
cholesterol determination are true except
a. There is less interference by non-sterol substance
b. It consumes microliter by quantities of sample
c. It is rapid and precise
d. A and B only
e. None of the above
d. A and B only
- Which of the following methods are used for lipoprotein estimation?
a. Ultracentrifugation
b. Electrophoresis
c. Polyanion precipitation method
d. A and B only
e. All of the above
e. All of the above
- The following statements about lithium are true except
a. It is present in normal tissues in trace amount
b. It is excreted entirely by urine
c. It is preferred treatment for bipolar disorder particularly manic phase
d. Its serum concentration can be determined by flame photometry
b. It is excreted entirely by urine
- Which of the following is considered as “good” cholesterol?
a. LDL
b. HDL
c. VLDL
d. Chylomicrons
e. sphingolipids
b. HDL
- Which of the following is the method of choice for serum calcium determination?
a. Spectrophotometry
b. Flame photometry
c. Flurometry
d. Atomic absorption
e. Clark & Collip technique
d. Atomic absorption
- Which of the following is use to determine the state of glycemia in diabetic patients over the preceding 8-12 weeks?
a. Fasting plasma glucose
b. Random blood sugar
c. Glycosylated hemoglobin(HbA1c)
d. Serum fructosamine
e. None of the above
c. Glycosylated hemoglobin(HbA1c)
- Which of the following plasma proteins binds to hemoglobin?
a. Haptoglobin
b. Albumin
c. C3
d. Fibrinogen
e. Antitrypsin
a. Haptoglobin
- Which of the following isoenzymes of creatinine kinase is more specific in the diagnosis of acute myocardial infarction?
a. CK1 or BB
b. CK2 or MB
c. CK3 or MM
d. A & B
e. B & C
b. CK2 or MB
- An increased incidence of urinary cast formation is associated with
a. Acidic urine
b. Concentrated urine
c. Proteinuria
d. All of the above
e. A and B only
d. All of the above
- Which of the following condition can result in elevated CSF protein?
a. Traumatic tap
b. Blood brain barrier damage
c. Neural tissue degeneration
d. All of the above
e. A and B only
d. All of the above
- The main function of the glomerulus is the conservation of
a. Blood cells
b. Most proteins
c. Electrolytes
d. A and B only
e. B and C only
d. A and B only
- The standard laboratory test used to detect early stages of renal failure measures.
a. Creatinine clearance
b. Creatinine
c. Blood urea nitrogen
d. Serum uric acid
e. Fixed urine osmolarity
a. Creatinine clearance
- ACTH is correctly describes as
a. Produced in the adrenal cortex
b. Inhibited by catecholamines
c. Stimulating production of cortisol by adrenal cortex
d. Not showing diurnal variation as does cortisol
e. stimulated by dexamethasone
c. Stimulating production of cortisol by adrenal cortex
- An increase in plasma unconjuagated bilirubin may be casused by?
a. Increased hemolysis
b. Certain drugs
c. Generic errors
d. All of the above
e. A and B only
d. All of the above
- A 70 year old woman who presents with hematuria, casts, azotemia, and isothenuria suggest a diagnosis of
a. Nephrotic syndrome
b. Pyenlonephritis
c. Acute renal failure
d. Polycystic kidney
e. Renal cell carcinoma
a. Nephrotic syndrome
- The therapeutic range of drugs in plasma is
a. The range of concentration within which the drug is effective yet not toxic
b. Dependent on an assessment of clinical response
c. Independent of the presence of other disease
d. A and B only
e. B and C only
d. A and B only
- Ceruloplasmin is a plasma protein that binds
a. Chromium
b. Copper
c. Zinc
d. Lead
e. iron
b. Copper
- The primary storage form of iron is
a. Apotransferrin
b. Transferrin
c. Ferritin
d. Hemosiderin
e. myoglobin
c. Ferritin
- Which of the following is normally present in serum but must be chemically removed so that it will not interfere with measurement of serum magnesium?
a. Calcium
b. Chloride
c. Iron
d. Potassium
e. sodium
a. Calcium
- The presence of slightly visible hemolysis can significantly increase the
serum level of
a. Sodium
b. Potassium
c. Chloride
d. Bicarbonate
e. calcium
b. Potassium