12.3 DNA Replication Flashcards
special sites where replication
begins.
Replication origins
the process in which DNA copies itself (duplicates).
Replication of DNA
The combination of DNA and proteins is called a
Replisome
enzyme that begins the replication process by attaching to a DNA molecule and breaking the hydrogen bonds between the nitrogen bases. DNA helicase moves along the molecule and “unzips” the two strands of DNA.
DNA Helicase
enzyme that catalyzes the formation of the sugar-to-phosphate bonds that connect one nucleotide to the next one.
DNA Polymerase
covalently joins the Okazaki fragments on the lagging strand.
DNA Ligase
is the enzyme that adds a short stretch of RNA (about 5 nucleotides long) that acts as an RNA primer.
Primase
help keep the DNA strands separated.
Single-stranded binding proteins
Any change in the sequence of a cell’s DNA is
known as a
Mutation