12 - Drugs & Polypharmacy 3 Flashcards

1
Q

define deprescribing?

A

to reduce, substitute or discontinue a drug

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2
Q

4 reasons for deprescribing?

A

Adverse drug reaction

Drug-drug interaction

Better alternative

Not effective

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3
Q

name top 3 drugs which are associated with admission due to adverse drug reaction?

A

NSAIDs

diuretics

Warfarin

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4
Q

name 4 common side effects of antimuscarinics?

A

dry mouth/ eyes

constipation

reduced peristalsis

urinary retention

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5
Q

name 2 GI antispasmodics?

antimuscarinic

A

dicycloverine hydrochloride

hyoscine butylbromide

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6
Q

name 2 drugs for overactive bladder?

antimuscarinic

A

oxybutynin hydrochloride

tolterodine tartrate

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7
Q

name 2 tricyclic antidepressants?

antimuscarinic

A

amitriptyline hydrochloride

dosulepin hydrochloride

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8
Q

name 2 sedating antihistamines?

antimuscarinic

A

chrlopheniramine maleate

hydroxyzine hydrochloride

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9
Q

name 2 antiemetics? (antimuscarinic)

A

prochlorperazine

hyoscine hydrobromide

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10
Q

name 2 antipsychotics? (antimuscarinic)

A

haloperidol

chlorpromazine hydrochloride

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11
Q

name 4 nonclassical muscarinic drugs?

A

ranitidine
phenytoin
citalopram
lithium

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12
Q

what can be used to assess risks of anticholinergic meds?

A

Anticholinergic risk scale

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13
Q

in terms of psychiatric treatment, are sedatives effective?

A

they can be problematic - increased risks of falling and confusion

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14
Q

in terms of psychiatric treatment, are anti-psychotics effective?

A

they can have increased adverse effects - postural hypotension, stroke, confusion, movement disorders

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15
Q

name 2 opioids which may be less useful in treating older people?

A

tramadol

pethidine

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16
Q

name 2 adverse effects of NSAIDs?

A

renal impairment

GI bleeding

17
Q

what can diuretics cause?

A

abnormal urea and electrolytes

18
Q

2 risks associated with using warfarin?

A

GI bleeding

falls

19
Q

name 4 potential adverse effects of antibiotics?

A

diarrhoea
c. diff infection
delirium
seizures