12 - Drugs & Polypharmacy 3 Flashcards
define deprescribing?
to reduce, substitute or discontinue a drug
4 reasons for deprescribing?
Adverse drug reaction
Drug-drug interaction
Better alternative
Not effective
name top 3 drugs which are associated with admission due to adverse drug reaction?
NSAIDs
diuretics
Warfarin
name 4 common side effects of antimuscarinics?
dry mouth/ eyes
constipation
reduced peristalsis
urinary retention
name 2 GI antispasmodics?
antimuscarinic
dicycloverine hydrochloride
hyoscine butylbromide
name 2 drugs for overactive bladder?
antimuscarinic
oxybutynin hydrochloride
tolterodine tartrate
name 2 tricyclic antidepressants?
antimuscarinic
amitriptyline hydrochloride
dosulepin hydrochloride
name 2 sedating antihistamines?
antimuscarinic
chrlopheniramine maleate
hydroxyzine hydrochloride
name 2 antiemetics? (antimuscarinic)
prochlorperazine
hyoscine hydrobromide
name 2 antipsychotics? (antimuscarinic)
haloperidol
chlorpromazine hydrochloride
name 4 nonclassical muscarinic drugs?
ranitidine
phenytoin
citalopram
lithium
what can be used to assess risks of anticholinergic meds?
Anticholinergic risk scale
in terms of psychiatric treatment, are sedatives effective?
they can be problematic - increased risks of falling and confusion
in terms of psychiatric treatment, are anti-psychotics effective?
they can have increased adverse effects - postural hypotension, stroke, confusion, movement disorders
name 2 opioids which may be less useful in treating older people?
tramadol
pethidine