Pharmacology, Fluids, Electrolytes Flashcards

1
Q

What is the loading dose of caffeine?

A

20 mg/kg

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2
Q

What is the maintenance dose of caffeine?

A

5-10 mg/kg/day

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3
Q

What is pharmacodynamics?

A

What a drug does in the body/how the body is affected by a drug

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4
Q

What is pharmacokinetics?

A

How a drug moves through and behaves in the body (absorption, distribution, metabolism, elimination)

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5
Q

How do you calculate GIR?

A

((% dextrose x hourly rate x 0.167) / (wt in kg))

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6
Q

What is the initial fluid goal for a preterm neonate?

A

60-80 ml/kg/day

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7
Q

What is Insensible Water Loss (IWL) and how can it be reduced?

A

IWL is the evaporation of water through skin, mucous membranes, and respiratory tract

  • Double-walled, humidified isolettes
  • Semipermeable skin coverings
  • Pre-warming of surfaces
  • Inspiring warm air (HFNC)
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8
Q

What is normal urine output by the third day of life in neonates with normal kidneys?

A

1-3 ml/kg/hour

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9
Q

What is the recommended daily maintenance fluid requirements during the first 2 days of life for a baby born <750g?

A

100-200 ml/kg/day

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10
Q

What is the recommended daily maintenance fluid requirements between days of life 3 and 7 for a baby born <750g?

A

120-200 ml/kg/day

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11
Q

What is the recommended daily maintenance fluid requirements during the first 2 days of life for a baby born 750-1000g?

A

80-150 ml/kg/day

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12
Q

What is the recommended daily maintenance fluid requirements during the first 2 days of life for a baby born 1001-1500g?

A

60-100 ml/kg/day

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13
Q

What is the recommended daily maintenance fluid requirements during days of life 3-7 for a baby born 750-1000g?

A

100-150 ml/kg/day

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14
Q

What is the recommended daily maintenance fluid requirements during days of life 3-7 for a baby born 1001-1500g?

A

80-150 ml/kg/day

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15
Q

What is the normal initial GIR to promote euglycemia in preterm neonates?

A

4-6 mg/kg/min

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16
Q

What is the suggested response to a blood glucose of <45 mg/dL?

A

Bolus of 200 mg/kg (2 ml/kg) D10W

17
Q

What is the recommended protein intake for VLBW neonates for optimal growth and protein accretion?

A

3-3.5 g/kg/day (max 4)

18
Q

What is the recommended dose of IV lipids to prevent increased lipolysis and essential fatty acid deficiency?

A

Minimum of 0.5-1 g/kg/day

19
Q

What is the recommended dose of epinephrine at 1:10000 concentration?

A

0.1-0.3 per kg