11/14 Flashcards
what does an ester with NaOH and H20 do?
it undergoes base-promoted hydrolysis to form a carboxylate salt
how do we reduce an ester to an alcohol
LAH
how do we reduce an ester to an aldehyde
with DIBAL-H
can NaBH4 be used to reduce an ester
no
how does a grignard react with esters
two equivalents to make a tertiary alcohol
what stype of reaction is the first addition of grignard to an ester
nucleophillic acyl substitution
what type of reaction is the second addition of grignard to an ester
nucleophillic addition
what do amides form when linked together
a peptide bond, it forms the basis of life
what does a carboxylic acid, DCC and RNH2 form
it forms an amide
what is the purpose of DCC in amide synthesis
it makes OH into a good LG
why are nitriles useful
they can be converted into carboxylic acids
what is one intermediate in the acidic synthesis of a nitrile to a carboxylic acid
an imine
is there a proton transfer in imine formation
yes
is there a proton transfer in acetal formation
no
is there proton transfer in enamine formation
yes
