1. AntiMalarial Drugs

Question 1

Malaria Cycle

Answer 1

Page 496

Question 2

Prevent relapse / Radical cure / Terminal prophylaxis

Answer 2

Primaquine x 14 days / Tafenoquine -once ( not pyrimethamine )

Question 3

Inhibit transmission of malaria [ Gamatocidal ]

Answer 3

Primaqine , Artemisisinin group

Question 4

Symptomatic relief ( erythocytic Schizontocidal )

Answer 4

Fast and slow acting

Question 5

Primaquine acts on which stages

Answer 5

All

Question 6

Artemisinin groups of drugs :-

1. Classification
2. MOA
3. CI
4. Uses
5. Importants

Answer 6

Page 498

Question 7

Artemisinin combination therapy for uncomplicated malaria

Answer 7

Page 498

Question 8

Uncomplicated malaria in pregnancy

Answer 8

499

Question 9

Side effects of artemisinin group

Answer 9

499

Question 10

Prophylaxis for malaria ( endemic area )

Answer 10

499

Question 11

WHO combinations

Answer 11

499

Question 12

Loading dose is essential for primaquine bcoz

Answer 12

High volume of distribution

Question 13

Drugs used in treatment of P. viva malaria in pregnancy :-

Answer 13

1. DOC
2. If resistant
3. 2 and 3 trimester

Question 14

Chloroquine

1. MOA
2. Uses
3. Sideeffect

Answer 14

500

Question 15

Animalarial causing bulls eye maculopathy

Answer 15

500

Question 16

Quinine

MOA
Uses
Side effect

Answer 16

Alpha 1 blocker 
B stimulator in pancreases 
Cinchonism 
K+ channel blocker 
Black water fever

Question 17

Tetracycline/ Doxycycline/ clindamycin

Answer 17

501

Question 18

Mefloquine
Uses
Side effect

Answer 18

Neuropsychiatric side effect

Cardiac conduction defect

Question 19

Atovaquone + proguanil
MOA
Uses

Answer 19

502

Question 20

Uses of atovaquone

Uses of proguanil

Answer 20

502

Question 21

Primaquine
Acts on stages
SE
CI

Answer 21

502

Question 22

Tafenoquine
Use
SE
CI

Answer 22

503