1 Flashcards
What is a pathogen?
An organism that can cause infection
What is an infection?
Multiplication of pathogens in or on a host with reaction of host tissues
What is a disease?
Disturbance of normal host function
What is an infectious disease?
An infection where the host reacts to a pathogen meaning host cells can’t carry out normal functions (often communicable)
What is contamination?
Temporary presence of organisms in a location/env WITHOUT reaction/injury
What is colonisation?
Continued presence of organisms in a location/env WITHOUT reaction/injury
Why is hygienic practice important?
Prevent spread of communicable diseases
Why do we want to prevent communicable diseases spreading?
-Mortality (death)
-Expensive
More beds taken
More treatment needed
Patient more unwell (if HCAI)
What are health care acquired infections?
Infectious diseases acquired more than 48h after admission OR less than 48h after discharge
What are some common HCAIs?
-UTIs
-Pneumonia/other resp tract infections
Surgical site infection
-Gastroenteritis
-C.Difficile
What are the 7 modes of transmission for infectious diseases & give examples?
-Airbourne - respiratory droplets in air (COVID-19)
-Direct contact - touch each other (MRSA)
-Indirect contact - touch things they have (MRSA)
-Fecal-oral (C.Difficile)
-Blood borne (Hepititis)
-Vector - animals, insects, rodents (Malaria)
-Vertical - via placenta (HIV)
What is the most effective place to break the chain of infection?
Modes of transmission
How do detergent disinfectants work?
-Hydrophobic part sticks to hydrophobic oils & microorganisms
-Hydrophilic part = so can be easily rinsed away
–> on ALL microorganisms
How do alcoholic disinfectants work?
-Dissolve cell memb & denatures prots in memb
–> on SOME microorganisms (not C.diff - as has spores)
How do chlorine sterilising agents work?
-Dissolves cell memb - as +ve charge of agent binds to parts of microorganism
-Works on inner mems too
–> on ALL microorganisms