(02) Differential Diagnosis of Pigment

Question 1

Differentiate Cholestasis from Hemochromatosis.

Answer 1

Hemochromatosis:

• Pigment - More Brown
• AST and ALT are elevated

Cholestasis:

• Pigment - green, gold, orange, yellow
• Abnomal Serum Bilirubin

Question 2

Differentiate Hemosiderosis and Hemochromatosis.

Answer 2

Hemochromatosis:
- Pigment accumulated IN the hepatocytes

Hemosiderosis:
- Hemosiderin is accumulated in the Kuppfer cells

Question 3

Differentiate Lipofuscin and Hemochromatosis?

Answer 3

Hemochromatosis:
- Elevated ALT and AST

Lipfuscin:
- No elevation of liver enzymes

Question 4

Diffentiate Hemochromatosis and metastatic melanoma?

Answer 4

Hemochromatosis:
- Cells will still be liver cells

Metastatic Melanoma:
- Cells will be darker and will be skin cells